Combined Thyroxine/Liothyronine Treatment Does Not Improve Well-Being, Quality of Life, or Cognitive Function Compared to Thyroxine Alone: A Randomized Controlled Trial in Patients with Primary Hypothyroidism
نویسندگان
چکیده
منابع مشابه
Combined levothyroxine plus liothyronine compared with levothyroxine alone in primary hypothyroidism: a randomized controlled trial.
CONTEXT Standard therapy for patients with primary hypothyroidism is replacement with synthetic thyroxine, which undergoes peripheral conversion to triiodothyronine, the active form of thyroid hormone. Within the lay population and in some medical communities, there is a perception that adding synthetic triiodothyronine, or liothyronine, to levothyroxine improves the symptoms of hypothyroidism ...
متن کاملCombined therapy with L-thyroxine and L-triiodothyronine compared to L-thyroxine alone in the treatment of primary hypothyroidism.
OBJECTIVE The objective of this study was to compare various parameters in patients with hypothyroidism receiving either monotherapy with L-thyroxine (L-T4) or combination therapy with L-T4 and L-triiodothyronine (L-T3). DESIGN We conducted a randomized, controlled trial in 36 premenopausal women with hypothyroidism. The patients were divided into two groups: Group A (n=20) received only L-T4...
متن کاملCognitive functioning and well-being in euthyroid patients on thyroxine replacement therapy for primary hypothyroidism.
OBJECTIVE Hypothyroidism is associated with neurocognitive impairment. Sparse data suggest that treatment of hypothyroidism, resulting in a return to euthyroidism, may be associated with only partial recovery of overall neurocognitive functioning. The aim of this study was to assess neurocognitive functioning and well-being in euthyroid patients with primary hypothyroidism on adequate thyroxine...
متن کاملEffect of a Quality of Life Education Program on Psychological Well-Being and Adherence to Treatment of Diabetic Patients
Abstract Introduction: Diabetes is a chronic disease with fatal health complications. Identifying the psychological factors that control this disease is very important, one of which is quality of life (QOL). Objective: This study aimed to investigate the effect of a QOL education program on psychological well-being (PWB) and adherence to treatment of patients with type 2 diabetes. Materials ...
متن کاملTraining Mothers to Improve Gross Motor Skills in Children With Cerebral Palsy: A Randomized Controlled Trial
Objectives: The present study examined the effect of home-based handling training of mothers on the improvement of gross motor function of children with Cerebral Palsy (CP). Methods: In this randomized control trial, 42 children with CP (5-12 years old) were randomly assigned into the intervention and control groups. Data were collected using the Gross Motor Function Classification System and ...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2003
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2003-030249